吳啟豪

期刊論文

年度	論文名稱
2018	Lin JA, Wu CH*, Yen GC., Perspective of Advanced Glycation End Products on Human Health, J Agric Food Chem., 66, 9, pp2065-2070, (SCI)
2018	Lin JA, Wu CH, Yen GC., Methylglyoxal displays colorectal cancer-promoting properties in the murine models of azoxymethane and CT26 isografts, Free Radic Biol Med., 115, pp436-446
2017	Wang, T. H., Wu, C. H., Yeh, C. T., Su, S. C., Hsia, S. M., Liang, K. H., Chen, C. C., Hsueh, C. and Chen, C. Y., Melatonin suppresses hepatocellular carcinoma progression via lncRNA-CPS1-IT-mediated HIF-1α inactivation., Oncotarget, 8, 47, pp82280-82293, (SCI)
2017	Lin, L. C., Wu, C. H.*, Shieh, T. M., Chen, H. Y., Huang, T. C. and Hsia, S. M., The licorice dietary component isoliquiritigenin chemosensitizes human uterine sarcoma cells to doxorubicin and inhibits cell growth by inducing apoptosis and autophagy via inhibition of m-TOR signaling., J. Funct. Foods, 33, pp332-344, (SCI)
2017	Lin, J. A., Wu, C. H.*, and Yen, G. C., Breadfruit flavonoid derivatives attenuate advanced glycation end products （AGEs）-enhanced colon malignancy in HCT116 cancer cells., J. Funct. Foods, 31, pp248-254, (SCI)
2017	Yeh, W. J., Hsia, S. M., Lee, W. H. and Wu, C. H.*, Polyphenols with anti-glycation activity and mechanisms of action: review of recent findings., J. Food Drug. Anal., 25, pp84-92, (SCI)
2017	Wu, C. H., Chen, H. Y., Wang, C. W., Shieh, T. M., Huang, T. C., Lin, L. C., Wang, K. L. and Hsia, S. M. , Isoliquiritigenin induces apoptosis and autophagy and inhibits endometrial cancer growth in mice., Oncotarget, 7, 45, pp73432-73447, (SCI)
2016	Hsia, S. M., Lee, W. H., Yen, G. C. and Wu, C. H.*, Capsaicin, an active ingredient from chilli peppers, attenuates glycative stress and restores sRAGE levels in diabetic rats., J. Funct. Foods, 21, pp406-417, (SCI)
2016	Lin, J. A., Wu, C. H., Lu, C. C., Hsia, S. M. and Yen GC, Glycative stress from advanced glycation end products （AGEs） and dicarbonyls: An emerging biological factor in cancer onset and progression., Mol. Nutr. Food Res., 60, 8, pp1850-1864, (SCI)
2015	Wu, C. H.*, Shieh, T. M., Wang, K. L., Huang, T. C. and Hsia, S. M. , Quercetin, a main flavonoid in onion, inhibits the PGF2α-induced uterine contraction in vitro and in vivo., J. Funct. Foods, 19, pp495-504, (SCI)
2015	Chang, W. T., Wu, C. H.* and Hsu, C. L., Diallyl trisulphide inhibits adipogenesis in 3T3-L1 adipocytes through lipogenesis, fatty acid transport, and fatty acid oxidation pathways., J. Funct. Foods, 16, pp414-422, (SCI)
2015	Wu, C. H., Hon, B. H., Ho, C. T. and Yen, G. C., Targeting cancer stem cells in breast cancer: the potential anticancer properties of 6-shogaol and pterostilbene., J. Agric. Food Chem., 63, pp2432-2441, (SCI)
2015	Wu, C. H., Chen, A. Z. and Yen, G. C., Protective effects of glycyrrhizic acid and 18β-glycyrrhetinic acid against cisplatin-induced nephrotoxicity in BALB/c mice., J. Agric. Food Chem., 63, pp1200-1209, (SCI)
2014	Wu, C. H., Chen, M. J., Shieh, T. M., Wang, K. L., Wu, Y. T., Hsia, S. M. and Chiang, W., Potential benefits of adlay on hyperandrogenism in human chorionic gonadotropin-treated theca cells and a rodent model of polycystic ovary syndrome., J. Funct. Foods, 11, pp393-406, (SCI)
2014	Huang, D. W., Wu, C. H.*, Shih, C. K., Liu, C. Y., Shih, P. H. Shieh, T. M. Lin, C. I., Chiang, W. C. and Hsia, S. M., Application of the solvent extraction technique to investigation of anti-inflammatory activity of adlay bran., Food Chem., 145, pp445-453, (SCI)
2014	Kao, T. C., Wu, C. H. Yen, G. C., Bioactivity and potential health benefits of licorice., J. Agric. Food Chem., 62, pp542-553, (SCI)
2013	Wu, C. H., Hsieh, H. T., Lin, J. A. and Yen, G. C., Alternanthera paronychioides protects pancreatic β-cells from glucotoxicity by its antioxidant, antiapoptotic and insulin secretagogue actions. , Food Chem., 139, pp362-370, (SCI)
2013	Hong, B. H., Wu, C. H., Yeh, C. T. and Yen, G. C., Invadopodia-associated proteins blockade as a novel mechanism for 6-shogaol and pterostilbene to reduce breast cancer cell motility and invasion., Mol. Nutr. Food Res., 57, pp886-895, (SCI)
2013	Kao, T. C., Wu, C. H. and Yen, G. C., Glycyrrhizic acid and 18β-glycyrrhetinic acid recover glucocorticoid resistance via PI3K-induced AP1, CRE and NFAT activation., Phytomedicine, 20, pp295-302, (SCI)
2013	Cheng, Y. T., Wu, C. H., Ho, C. Y. and Yen, G. C., Catechin protects against ketoprofen-induced oxidative damage of the gastric mucosa by up-regulating Nrf2 in vitro and in vivo. , J. Nutr. Biochem., 24, pp475-483, (SCI)
2011	Wu, C. H., Huang, H. W., Huang, S. M., Lin, J. A., Yeh, C. T. and Yen, G. C., AGE-induced interference of glucose uptake and transport as a possible cause of insulin resistance in adipocytes. , J. Agric. Food Chem., 59, pp7978-7984, (SCI)
2011	Wu, C. H., Huang, H. W., Lin, J. A., Huang, S. M. and Yen, G. C. , The pro-glycation effect of caffeic acid leads to the elevation of oxidative stress and inflammation in monocytes, macrophages and vascular endothelial cells., J. Nutr. Biochem., 22, pp585-594, (SCI)
2011	Wu, C. H., Huang, S. M. and Yen, G. C., Silymarin: a novel antioxidant with antiglycation and anti-inflammatory properties in vitro and in vivo., Antioxidants & Redox Signaling, 14, pp353-366, (SCI)
2011	Wu, C. H., Huang, S. M., Lin, J. A. and Yen, G. C. , Inhibition of advanced glycation endproducts formation by foodstuffs: a review., Food & Function, 2, pp224-234
2010	Wu, C. H., Yeh, C. T., Shih, P. H. and Yen G. C., Dietary phenolic acids attenuate individual stages of protein glycation and high glucose-stimulated proinflammatory IL-1β activation via interfering the chromatin remodeling and transc<x>ription in monocytes., Mol. Nutr. Food Res., 54, S2, pp127-140
2010	Wu, C. H., Yeh, C. T. and Yen, G. C., Epigallocatechin gallate （EGCG） binds to low-density lipoproteins （LDL） and protects them from oxidation and glycation under high-glucose conditions mimicking diabetes., Food Chem., 121, pp639-644, (SCI)
2009	Wu, C. H., Wu, C. F., Huang, H. W., Jao, R. C. and Yen, G. C. , Naturally occurring flavonoids attenuate high glucose-induced ex<x>pression of proinflammatory cytokines in human monocytic THP-1 cells., Mol. Nutr. Food Res., 53, pp984-995
2009	Hsu, C. L., Wu, C. H., Huang, S. L. and Yen, G. C. , Phenolic compounds rutin and o-coumaric acid ameliorate obesity induced by high-fat diet in rats., J. Agric. Food Chem., 57, pp425-431, (SCI)
2009	Wu, C. H., Lin, J. A., Hsieh, W. C. and Yen, G. C. , LDL-bound flavonoids increase the resistance of LDL to oxidation and glycation under pathophysiological concentrations of glucose in vitro., J. Agric. Food Chem., 57, pp5058-5064, (SCI)
2005	Wu, C. H. and Yen, G. C., Inhibitory effect of naturally occurring Flavonoids on advanced glycation endproducts formation., J. Agric. Food Chem. , 53, pp3167-3173, (SCI)
2004	Wu, C. H. and Yen G. C., Antigenotoxic properties of Cassia tea （Cassia tora L.）: mechanism of action and the influence of roasting process., Life Sci., 76, pp85-101, (SCI)
2001	Wu, C. H., Hsieh, C. L., Song, T. Y. and Yen, G. C., Inhibitory effects of Cassia tora L. on Benzo[a]pyrene-mediated DNA damage toward HepG2 cells. , J. Agric. Food Chem. , 49, pp2579-2586, (SCI)
1999	吳啟豪、顏國欽, 決明子水萃取物抑制B[a]P及IQ化合物致突變性之研究, 中國農業化學會誌, 37, 2, pp263-275, (Others)

專書/專書章節

年度	書名
2004	Herbal and traditional medicine: molecular basis in health and disease management, Antioxidant properties and antigenotoxicity of Cassia tora L. , Marcel Dekker, 978-0824-752088
2002	Free Radicals in Foods: Chemistry, Nutrition, and Health Effects, Effect of roasting process on the antioxidant properties of Cassia tora L., American Chemical Society, 978-0841-237414

研究計畫

年度	計畫名稱	參與人	職稱/擔任之工作	計畫期間	補助/委託或合作機構
2017	薏苡殼及其機能性成分之抗醣化生物活性	吳啟豪	主持人	2017.08 ~ 2018.07	科技部
2014	糖毒素對攝護腺癌惡性程度之促進效應	吳啟豪	主持人	2014.08 ~ 2017.07	科技部
2014	食品安全人才培訓計畫	吳啟豪	協同主持人	2014.01 ~ 2014.12	衛福部
2014	食品安全守護聯盟計畫	吳啟豪	協同主持人	2014.01 ~ 2015.12	衛福部
2013	類鐸受體訊息傳遞途徑在中風致病機轉及預後所扮演之角色-探討缺血性中風病患之類鐸受體相關微型核糖核酸表現	吳啟豪	主持人	2013.08 ~ 2015.07	科技部
2012	辣椒素對高度醣化終產物生成之抑制潛力	吳啟豪	主持人	2012.12 ~ 2014.07	國科會

學歷

國家	學校名稱	系所	學位	期間
中華民國	國立中興大學	食品暨應用生物科技學系	博士	2002.09 ~ 2009.06

經歷

服務機關名稱	單位	職務	期間
臺北醫學大學	保健營養學系	副教授	2016.02 ~ 2017.01
臺北醫學大學	保健營養學系	助理教授	2012.08 ~ 2016.01
臺北醫學大學	醫學科學研究所	博士後研究員	2011.08 ~ 2012.07
台中榮民總醫院	教學研究部	博士後研究員	2010.08 ~ 2011.07
國立中興大學	食品暨應用生物科技學系	博士後研究員	2009.08 ~ 2010.07